Kenneth ChengMathematical modeling

Editorial project overview

Genetic Drift, Selection, and Migration

When do drift, selection, migration, and bottlenecks dominate the fate of a new allele and the diversity around it?

Reproducible studyUpdated 30 Jul 2026
Technical figure from Genetic Drift, Selection, and Migration
A reviewed research figure synchronized from the private technical workspace. The original aspect ratio and labels are preserved.

Editorial overview

Read When Randomness Defeats Natural Selection for the four biological clocks, theory-as-test comparisons, migration balance, bottleneck memory, four approved figures, and a careful separation of process, Monte Carlo, and model uncertainty.

Key findings

  • A selection coefficient of 0.05 raised fixation to about 0.09–0.10, so most new beneficial copies still disappeared.
  • A ten-generation bottleneck from 500 to 10 left final heterozygosity near 0.252, versus about 0.417 without the bottleneck.

Limitations

  • These are idealized Wright–Fisher experiments, not estimates for a named population.
  • Linked selection, mutation during fixation runs, and genomic ascertainment are outside scope.

Technical record

Detailed source, calculations, generated figures, and reproduction instructions are maintained in a private technical workspace. Public articles contain only manually reviewed interpretation and approved figures.

Version history

2026-07-30 — Curated overview reviewed against repository evidence.